Jose E Tanus-Santos Selected Research

Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)

1/2018	Endothelial nitric oxide synthase polymorphisms affect the changes in blood pressure and nitric oxide bioavailability induced by propofol.
2/2017	Clinical and pharmacogenetic impact of endothelial nitric oxide synthase polymorphisms on cardiovascular diseases.
1/2016	Endothelial nitric oxide synthase tagSNPs influence the effects of enalapril in essential hypertension.
6/2012	Endothelial nitric oxide synthase polymorphism rs3918226 associated with hypertension does not affect plasma nitrite levels in healthy subjects.
6/2011	Endothelial nitric oxide synthase haplotypes associated with aura in patients with migraine.
9/2010	Vascular endothelial growth factor (VEGF) and endothelial nitric oxide synthase (NOS3) polymorphisms are associated with high relapse risk in childhood acute lymphoblastic leukemia (ALL).
4/2010	Endothelial nitric oxide synthase haplotypes associated with hypertension do not predispose to cardiac hypertrophy.
10/2008	eNOS haplotypes associated with gestational hypertension or preeclampsia.
5/2007	Influence of eNOS haplotypes on the plasma nitric oxide products concentrations in hypertensive and type 2 diabetes mellitus patients.
12/2006	Endothelial nitric oxide synthase genotype and haplotype are not associated with diabetic retinopathy in diabetes type 2 patients.

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Jose E Tanus-Santos Research Topics

Disease

62	Hypertension (High Blood Pressure) 09/2021 - 02/2002
28	Pulmonary Embolism 10/2021 - 01/2002
26	Pre-Eclampsia (Preeclampsia) 01/2021 - 07/2008
25	Cardiovascular Diseases (Cardiovascular Disease) 03/2020 - 07/2002
16	Pulmonary Hypertension 10/2021 - 01/2002
14	Renovascular Hypertension (Goldblatt Syndrome) 02/2018 - 10/2002
12	Vascular Remodeling 01/2021 - 06/2008
11	Thrombosis (Thrombus) 10/2021 - 07/2002
9	Cardiomegaly (Heart Hypertrophy) 03/2020 - 04/2010
9	Hypertrophy 12/2015 - 09/2008
8	Hypotension (Low Blood Pressure) 02/2022 - 09/2005
8	Pregnancy-Induced Hypertension (Hypertension, Pregnancy Induced) 08/2016 - 07/2008
6	Migraine Disorders (Migraine) 01/2013 - 07/2010
5	Erectile Dysfunction 12/2015 - 09/2004
5	Fibrosis (Cirrhosis) 10/2015 - 10/2002
4	Hemolysis 01/2014 - 12/2002
4	Chronic Kidney Failure (Chronic Renal Failure) 12/2012 - 01/2011
3	Pediatric Obesity 01/2015 - 07/2009
3	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 08/2014 - 12/2010
3	Epilepsy (Aura) 01/2013 - 06/2011
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2013 - 12/2008
3	Type 2 Diabetes Mellitus (MODY) 05/2007 - 11/2006
2	Necrosis 01/2019 - 10/2002
2	Obesity 05/2015 - 09/2011
2	Periodontal Diseases (Periodontal Disease) 06/2013 - 11/2009

Drug/Important Bio-Agent (IBA)

65	Matrix Metalloproteinases (MMPs)IBA 01/2022 - 09/2005
40	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2022 - 01/2002
26	NitritesIBA 10/2021 - 12/2006
23	AntioxidantsIBA 10/2021 - 01/2006
23	Antihypertensive Agents (Antihypertensives)IBA 09/2021 - 12/2006
14	Sildenafil Citrate (Viagra)FDA Link 12/2015 - 09/2004
14	Matrix Metalloproteinase 9 (Gelatinase B)IBA 11/2012 - 09/2005
12	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 01/2018 - 11/2006
12	Doxycycline (Periostat)FDA LinkGeneric 01/2014 - 09/2005
9	Nitric Oxide Synthase (NO Synthase)IBA 02/2022 - 07/2002
9	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 05/2009
9	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 02/2009
9	Matrix Metalloproteinase InhibitorsIBA 01/2014 - 06/2010
8	APTIBA 10/2021 - 12/2006
8	Matrix Metalloproteinase 2 (Gelatinase A)IBA 03/2020 - 11/2005
8	Sodium NitriteIBA 01/2019 - 07/2011
7	tempolIBA 10/2021 - 05/2009
7	salicylhydroxamic acid (SHAM)IBA 03/2020 - 06/2008
7	Tissue Inhibitor of Metalloproteinase-2IBA 01/2015 - 07/2008
6	NitratesIBA 09/2021 - 12/2013
6	CollagenIBA 10/2015 - 05/2012
6	Hemoglobins (Hemoglobin)IBA 01/2014 - 12/2002
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2011
5	Biomarkers (Surrogate Marker)IBA 10/2019 - 02/2006
5	NG-Nitroarginine Methyl Ester (L-NAME)IBA 01/2018 - 10/2002
5	Atorvastatin (Lipitor)FDA Link 12/2015 - 09/2004
5	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 02/2014 - 12/2010
4	Vasodilator Agents (Vasodilators)IBA 10/2021 - 01/2002
4	Arginine (L-Arginine)FDA Link 09/2021 - 11/2005
4	Xanthine DehydrogenaseIBA 01/2021 - 06/2014
4	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2021 - 10/2016
4	Pharmaceutical PreparationsIBA 01/2016 - 03/2013
4	Eosine Yellowish-(YS) (Eosin)IBA 10/2015 - 02/2013
4	NADPH Oxidases (NAD(P)H oxidase)IBA 08/2015 - 07/2011
4	Troponin IIBA 03/2013 - 02/2008
4	Metalloproteases (Metalloproteinases)IBA 12/2012 - 06/2008
4	Tissue Inhibitor of MetalloproteinasesIBA 04/2012 - 02/2006
4	Tissue Inhibitor of Metalloproteinase-1IBA 08/2011 - 07/2006
4	lercanidipineIBA 01/2011 - 01/2006
3	Propofol (Diprivan)FDA LinkGeneric 02/2022 - 01/2018
3	EnzymesIBA 01/2022 - 01/2011
3	Transforming Growth Factors (Transforming Growth Factor)IBA 03/2020 - 02/2013
3	AnionsIBA 01/2019 - 12/2006
3	Losartan (Cozaar)FDA LinkGeneric 02/2018 - 02/2012
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 05/2017 - 09/2004
3	AdipokinesIBA 08/2016 - 02/2014
3	AdiponectinIBA 08/2016 - 08/2013
3	Thiobarbituric Acid Reactive SubstancesIBA 08/2016 - 10/2008
3	C.I. direct red 80IBA 10/2015 - 02/2013
3	Hematoxylin (Haematoxylon)IBA 08/2014 - 02/2013
3	Superoxides (Superoxide)IBA 06/2014 - 12/2013
3	CytokinesIBA 02/2014 - 07/2010
3	Peroxidase (Myeloperoxidase)IBA 06/2013 - 02/2010
2	Cell-Free Nucleic AcidsIBA 01/2021 - 11/2009
2	Nicotinamide PhosphoribosyltransferaseIBA 01/2021 - 05/2015
2	Omeprazole (Prilosec)FDA LinkGeneric 01/2021 - 10/2016
2	Tyrosine (L-Tyrosine)FDA Link 10/2019 - 08/2008
2	Messenger RNA (mRNA)IBA 01/2019 - 09/2008
2	S-NitrosothiolsIBA 01/2019 - 10/2015
2	aliskiren FDA Link 02/2018 - 08/2013
2	Renin InhibitorsIBA 02/2018 - 08/2013
2	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 05/2017 - 01/2011
2	Enalapril FDA LinkGeneric 01/2016 - 12/2012
2	Genetic Markers (Genetic Marker)IBA 05/2015 - 01/2011
2	Drinking WaterIBA 08/2014 - 05/2012
2	Nebivolol FDA Link 08/2014 - 12/2013
2	Metoprolol (Toprol-XL)FDA LinkGeneric 08/2014 - 12/2013
2	3-nitrotyrosineIBA 08/2014 - 12/2013
2	ElastinIBA 08/2013 - 05/2012
2	Tissue Plasminogen Activator (Alteplase)FDA Link 07/2013 - 06/2010

Therapy/Procedure

21	Therapeutics 01/2021 - 01/2002
20	Surgical Instruments (Clip) 09/2021 - 10/2002
4	Microspheres (Microsphere) 07/2013 - 09/2005
2	Anesthesia 01/2018 - 01/2018
2	Thrombolytic Therapy 07/2013 - 06/2010